Blood pressure control in intracerebral haemorrhage


Key points:

  1. well powered, international multi-centre randomised control, non-blinded trial
  2. primary hypothesis was that intensive blood pressure control with haemorrhagic stroke (SBP <140mmHg) would improve outcomes with regards to death and disability compared to standard BP targets (SBP <180mmHg)
  3. trial ended early due to futility (no statistical difference found)
  4. possible causes for lack of treatment effect include lower rate of death in standard BP target group compared to other literature (blunted treatment effect)

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