Thanks Dr An Le for his presentation on ethylene glycol toxicity.

 

Ethylene-Glycol-Poisoning-1

 

Key points:

1. key ingredient in antifreeze and other industrial products
2. any deliberate or significant ingestions are potentially lethal (>0.5ml/kg)
3. produces characteristic toxidrome with CNS depression, metabolic raised anion gap raised osmolar gap acidosis and potentially renal failure
4. antidote is ethanol
5. disposition is usually to HDU