Acid-base and Fluids

Acid-base and its practical application, according to the quantitative (Stewart) approach + the effects of fluids on acid-base.


  • pH is determined by the need for electrical neutrality
  • Strong ions and weak acids determine acid-base, not H+ and HCO3-
  • The Stewart approach allows you to quantify the contribution of different abnormalities¬†(e.g. lactate)¬†on metabolic acidosis
  • Fluids have an effect on acid-base – saline is strongly acidotic and therefore may not be the most sensible choice!

If you want to learn more on the ‘ideal’ generic fluid, have a read of this post by Josh Farkas on the Emcrit website.

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